QDIS Blog

A blog about chemistry, drug development, science, and technology

December 21, 2006

GlaxoSmithKline and Genmab Enter Global Agreement For HuMax-CD20

by @ 12:05 pm.  Filed under Pharma News

Seems the GlaxoSmithKline business development groups has been very busy lately. Earlier today I posted about GSK acquiring Praecis and before that they acquired Domantis. Now they are concentrating on deals and have entered into a large one with Genmab.

PharmaLive: GlaxoSmithKline and Genmab Enter Global Agreement For HuMax-CD20
GSK sign world’s-biggest licensing deal with Genmab:

This deal is worth $2.7 billion making it the largest deal that I know of (the Erbitux deal between Bristol-Myers Squibb and Imclone was $2 billion).

HuMax-CD20 (ofatumumab) is a human monoclonal antibody in phase III clinical trials for treatment of CD20 positive B-cell chronic lymphocytic leukemia and follicular non-Hodgkin’s lymphoma. Is it also being investigated in phase II trials for rheumatoid arthritis. Analysts (whose numbers I take with a block of salt) say the market for it could be $2-5 billion! GSK hopes to be able to fill an NDA for the compound sometime in 2008.

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